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There's a lot of great info here for you, but I will simply add that Zoloft has helped my mom, along with mirtazipine, as she suffers from a very anxiety-oriented dementia, coupled with depression. Mirtazipine was prescribed first, and Zoloft added several years later, but I think the combo may have been helpful from the beginning. An MRI was the first thing her (excellent) doctor did. And blood work, of course. Saw evidence of dementia on the MRI -- as well as minor stroke damage, which was not clinically significant, in his opinion. He DID explain all of this in clear English to my mom. My mom had a difficult life as well, but I believe her family history of dementia was more a predictor in her case than the chronic stress. She also had terrible sleeping patterns (like, very little sleep) in the years leading up to onset.

She has a great internist who is very familiar with dementia/Alz, and to this day, I have not subjected her to neuropsych testing or evaluation. But, due to clear family history, we did not have the doubts about her diagnosis like you do. I think more opinion(s) are appropriate in your case.

One more mention, in the early years, people with dementia will make valiant efforts to cover up their memory loss. Spend time with her and take notice of such tactics.
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heidiann: Imho, perhaps your mother SHOULD seek a second opinion physician since her PC physician seemed a bit short spoken/curt in her responses. Also, a geriatric neurologist could give her an M.R.I. of the head, which measures brain functionality. The medicine, Memantine "reduces the actions of chemicals in the brain that contribute to the symptoms of dementia," per Google.
If you feel a physician/specialist was ineffective, it's generally a good idea to seek a second opinion. True story = Last March, my former (and poor) urologist rx'd a medicine that had a rare side effect, pneumonia. It hospitalized me for four days. I sought a new urologist after I was discharged, of course.
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I do not know all the answers but I would seek a second opinion and perhaps keep quiet about the first set of results - as not to influence the new tests. Then compare notes and go from there. Does not sound good to me - more like increasing dementia which comes and goes and gets worse.
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I have worked in cognitive disorder clinics for many years in both Neurology and Geriatric clinics. I am not a doctor, I am a social worker but I have worked in these clinics for around 15 years so feel free to take this advice with that in mind.

I think some type of specialty Memory or cognitive clinic will give you the best comprehensive assessment. These are usually found connected to a Geriatric or Neurology practice for a major University center. I wish I could say that your diagnostic experience was rare but it is not. If you are not seeing a cognitive specialist many general PCPs do the minimum and then just start giving medications. The fact you were given the diagnosis of Major Neurocognitive disorder or "Dementia" states that a specific diagnosis has not been determined. These are catchall terms and do not denote a specific disease. Memantine is a medication that has been approved for Alzheimer's disease and has some benefit with Lewy Body Dementia but is generally used for someone in a Moderate stage of Dementia. Your mom sounds like she is only having mild symptoms based on your description. It is generally a very safe drug, with not a lot of side effects but it has also shown limited efficacy in earlier stages of dementia.

A "standard" cognitive workup usually entails an initial visit assessment (usually an hour to 1.5 hour appointment) where the provider looks at your overall medical picture, does a neurological exam and reviews your medications. They will then often order some basic labs, Neuropsych testing and an MRI. Medicare will generally cover Neuropsych testing only once a year so instead of getting a second Neuropsych opinion, I would take the testing reports you have to a specialist physician and let them interpret what they can from what was done. Our providers like to get a specialized MRI with Neuroquantative assessment that takes measurements of different parts of the brain that have to do with memory. With advancements in imaging, there are now "biomarkers" that can help distinguish different types of dementias, and depending on the findings of the MRI a specialist can decide if advanced imaging such as PET scans or a DAT scan are recommended. They can also help interpret the Neuropsych testing for you and put it in context with the other pieces of information.
A good diagnosis is made up of lots of pieces like a puzzle and it takes an engaged and specialized practitioner to take these tests, the family reports, the psych history, and their own assessments to come up with a good diagnosis.
Good luck
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My mom got both memantine and Zoloft (plus some others) at some point in her life. At least in her case they were crap and did more harm than good. If your mom is only having mild symptoms, as it seems according to what you say, I wouldn't give her any drug.
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The easiest way to diagnose dementia is to wait a year or two. If it's dementia, the symptoms will then be very obvious to anybody. In the early stages, the disease hasn't been consolidated and particularly lay people, won't notice anything unusual. A psychological diagnosis of neurocognitive disoder is highly suspicious of dementia. There are no laboratory tests that can diagnose dementia at the moment. If it's dementia, it will eventually emerge with all the characteristics. There is no cure for dementia regardless of the type. Medications for memory can't stop the dementia from progressing and killing the patient's brain before the rest of the body.
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Hi everyone, 

I’m sorry for not posting an update sooner. After Mom’s appointment, all of the emotions from the past few weeks (actually, months) came to a head and I needed to time to decompress. 

As I hoped, the scans came up all normal which was a huge relief. I KNOW that this does not rule out dementia, but at least I feel a bit better knowing that there is nothing more sinister at play (tumor, stroke etc) at this very moment. Also, it seems that the accompanying headaches are a pinched nerve so it’s a relief to have some clarity there, too.

In the end, the best result out of all of this is Mom feeling that there’s nothing “wrong” with her after all, along with a sense of vindication after being made to feel crazy by her DH.

Whether more progressive dementia symptoms rear their head over the passage of time is another conversation, but I’ve decided this is a conversation she does not need to be privy to until its no longer tenable. I want her to live her life as normal as possible - without any worry - for as long as possible.  

In the meantime, we will continue with the anti-depressants and see if things improve. I’m also working on getting her to seek talk therapy, encouraging her to get involved in more mood lifting activities and trying to get her away from the DH as often as possible. And I’ll just continue to observe.

So, for now, I’ll close the Dementia chapter and I’ll bookmark the page in case I need to revisit. I won’t leave this site entirely as there are many other things that I’ll be needing advice on (legal, future care etc) …. plus I’m sure I’ll need to vent about the DH now and again. And I promise to report back to share any developments should I start to see changes in her condition - either for the worse or the better.

Once again, I cannot thank you all enough for your genuine concern and warm, helpful advice. I’ve learned (and am still learning) so much from this space. Had I not come here, I would not have known where to even start or what I will need to look out for as time goes on. I know that I can’t prevent dementia, but I can at least work on being better prepared for what may come.

There are still some comments I want to reply to individually and I’ll do that in the coming days.

Thank you all again and much love. ❤️
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Llamalover47 Mar 2022
heidiann: Thank you for your update.
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Heidiann, all the best to you and Mom!
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Heidiann,

You should gather some information on gaslighting for your mom.

It sounds like that is what her husband does to make her question her own sanity.

Good news that the brain scan was clear, praise The Lord!
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There are many reasons not to take pharmaceuticals when we're ageing and our brains are heading into brain disease territory. Memory issues are not a normal part of ageing. Just because this 'seems' normal, because it happens to most folks, it is not.

I'm sure others have said that an MRI is next, but either way, the drugs aren't going to make a stitch of difference, they will in fact speed up any brain damage.

As soon as my mum's abusive husband died, her MS progression stopped in its track and hasn't progressed since. 7 years later.

The truth is there's not much medically that can be done to help your mum. I'd look into alternative therapies and improving her diet. Get her to drink more water and cut her fat/refined sugar intake, eat more organic fruit and vegetables and if possible, get away from the toxic health damaging abuser.
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lealonnie1 Mar 2022
There are many reasons TO take pharmaceuticals when we are aging, too. Your claim to be a 'dementia healer' and other comments to 'drink more water & eat more organic fruits & vegetables and less sugar' are pretty useless. My mother had progressive dementia, the real thing, and never took 'pharmaceuticals' in her life, ate healthy foods, no booze, no cigarettes, cooked meals from scratch, no desserts, did everything she was 'supposed' to do and STILL got dementia. All the 'eat right and exercise' hocus pocus is just that: hocus pocus. Genetics play a HUGE part in who winds up getting diagnosed with dementia/Alzheimer's later in life, regardless of what they ate!

Furthermore, memory issues ARE a part of normal aging! I have yet to meet ONE elder who's memory is as good as it was when they were 30-40 or 50! Fact. From the Alzheimer's website directly:

"Almost 40% of us will experience some form of memory loss after we turn 65 years old. But even if we experience memory loss, chances are still unlikely that we have dementia. For the most part, our memory loss is mild enough that we can still live our day-to-day lives without interruption.

Signs of memory loss as a part of normal aging
You're unable to remember details of a conversation or event that took place a year ago.
You're unable to remember the name of an acquaintance.
You forget things and events occasionally.
You occasionally have difficulty finding words.
You are worried about your memory, but your friends and relatives are not."

There are plenty of medications that CAN and DO help elders with their medical issues & many times where anti anxiety meds and/or anti depressants help an elder with dementia A LOT. To suggest that improving her diet at THIS stage of the game is going to do more than medications is even sillier than anything! Medication is not evil or the 'devil' and everyone should rely on their DOCTOR'S advice with such matters.
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